Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep807 | Obesity | ECE2016

Changes in SCD1 promoter DNA methylation after bariatric surgery in morbid obese patients are associated with free fatty acids levels

Morcillo Sonsoles , Martin-Nunez Gracia Ma , Garcia-Serrano Sara , Gutierrez-Repiso Carolina , Rodriguez-Pacheco Francisca , Ho-Plagaro Ailec , Alaminos-Castillo Miguel A , Valdes Sergio , Gonzalo Motserrat , Moreno-Ruiz Francisco J. , Montiel-Casado Custodia , Rodriguez-Canete Alberto , Garcia-Fuentes Eduardo

Introduction: Epigenetic is acquiring great importance in complex diseases, providing mechanisms whereby environmental factors can influence complex diseases such as obesity and type 2 diabetes. Experimental animal and human studies have revealed the association between SCD1 and obesity and insulin resistance. The aim of this study was to evaluate whether metabolic changes after intervention are associated with DNA methylation pattern and if these changes are related to weigh ...